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EmbryoCellect

EmbryoCellect

Pre Implantation Genetic Screening Kit

  • Initial attempts to detect aneuploidy in IVF embryos used FISH screening for a limited subset of chromosomes (5-12 chromosomes only).
  • Clinical data from these first attempts showed no benefit to IVF success rates.
  • This has changed dramatically since the introduction of advanced 24 chromosome preimplantation genetic screening (PGS).
  • PGS now assesses the loss or gain of any whole chromosomes.
  • Chromosome-specific PCR products from 120bp-4kb How are the printed: As a pooled library of sequences specific to each chromosome.
  • Number of array targets: Over 35 million.
  • On average 1.2m sequences per spot Replicate targets on chip: 1 spot per chromosome.
  • 8 replicates Microarrays per slide: 4 allowing the testing of 4 samples at a time Ease of analysis: There is a single spot per chromosome Software: Excel Macro.
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