IMSI-Strict combines Tygerberg Strict Criteria with motile sperm organelle morphology examination (MSOME) and provides software-based categorization using head size, head shape, mid-piece, and number of vacuoles. Using these analyzed parameters, sperm are assigned to one of three categories - normal, sub-normal or abnormal (see last page for detailed descriptions of each category).
Below video shows human sperm captured at high magnification for analysis using IMSI-Strict software.